Development of Pleiotropic TrkB and 5-HT4 Receptor Ligands as Neuroprotective Agents
One common event that is the most detrimental in neurodegenerative disorders, even though they have a complex pathogenesis, is the increased rate of neuronal death.Endogenous neurotrophins consist of the major neuroprotective factors, while brain-derived neurotrophic factor (BDNF) and its high-affinity tyrosine kinase receptor TrkB Medicated Oils a